BakersYeastBetaGlucan Health Informational Site

What is Beta 1, 3-D Glucan?

2011-05-31T15:31:00.001-05:00

What is Beta 1, 3-D Glucan?
Beta 1, 3-D Glucan from Baker's Yeast (Saccharomyces cerevisiae) is a pharmacological agent that enhances resistance to infection. Beta glucan has been shown to act through stimulation of immune cells. (Tsukagoshi, S. et al. 1984).

Glucans are long chain polysaccharide (sugar) molecules. Polysaccharides represent a structurally diverse class of macromolecules and have a high capacity for carrying biological information because of their great structural variability (like DNA).
Polysaccharides can interconnect at various points to form a wide range of branched or liner structures.
In nature there are many forms of these glucans.
Beta glucan is many glucose molecules joined in a specific way with branches called beta 1,3 linkages. These molecules have been shown to have specific stimulatory effects on the immune system. source

Transfer Point Beta Glucan with NPcaps

2011-05-03T20:06:00.001-05:00

Transfer Point Beta-1,3D Glucan
with NPcaps

Transfer Point uses NPcaps in their Beta-1,3D Glucan.
NPcaps capsules are an all-natural, two-piece non-animal capsule suitable for addressing a variety of cultural and dietary requirements, including those of vegetarians, diabetics and patients with restricted diets.
NPcaps capsules are made from pullulan, a water-soluble polysaccharide produced through a fermentation process. Widely used in Japan, pullulan is very stable and well-characterized, and has achieved broad regulatory acceptance around the world with its proven safety record.
NPcaps has been in commercial production for more than 25 years, having numerous uses in the food and pharmaceutical industries.
NPcaps pullulan capsules are odorless, tasteless, and completely biodegradable two-piece capsules made from this completely natural, vegetable-derived polysaccharide.
Because pullulan capsules are impermeable to oxygen transmission, NPcaps capsules are recommended for encapsulating oxidation-sensitive ingredients to provide enhanced protection.
Source: www.BakersYeastBetaGlucan.com (authorized distributor of Transfer Point Beta-1,3D Glucan)

Beta Glucan Anti Stress Report

2010-10-19T08:31:00.000-05:00

"Here is an interesting report published in Sept. 2010 on stress and cancer. I was particularly interested in the blocking of corticosterone and the phagocytosis. This research was done at Louisville University and in Europe. Glucan is the only supplement, a natural one, that I have taken along with my full Budwig protocol for prostate cancer. I took comfort in hearing about this along with what I had already read in researching the Beta Glucan. Below is a link to the report, which I recommend you read, and a short summary for those who don't want to read the research. My Transfer Point Beta Glucan supplier is offering a special now, so I included a link to that at the bottom for anyone interested." don
http://www.bakersyeastbetaglucan.com/AntiStressActionTransferPoint300BetaGlucan.pdf

"Numerous studies (currently more than 5,000 publications) have shown that beta glucans exhibit immune properties, including, antibacterial and anti-tumor activities.
As the glucans are more and more frequently used as an anti-stress agent, the University of Louisville along with the University Hospital Krc, Prague, Czech Republic, compared four commercially important glucans and their effect on stress.
While all four glucans showed some ability to inhibit stress-related inhibition, only glucan #300 from Transfer Point was able to return the phagocytosis to a normal level. Also, Transfer Point glucan #300 was able to completely block the stress-related increase in corticosterone release as well as keeping IL-6 and IL-12 secretion above control (PBS) levels." (click on above link to view complete report dated Sept. 2010)

Stress is a physical, chemical, or emotional factor that causes bodily or mental tension and may be a factor in disease causation. It can be defined as a reation to any stimulus or interference that upsets normal functioning and disturbs mental or physical health. It can be brought on by internal conditions, such as illness, pain, or emotional conflict, or by external circumstances such as a death in the family or financial problems. Even a positive experience-a new marriage-can be a stress provoking event. Currently, between 70 and 80 percent of all visits to physicians are for stress-related disorders. Chronic stress directly affects the immune system, and if not effectively dealt with, can seriously compromise your health.

Along with your first order of Transfer Point Beta Glucan, glucan #300, from www.BakersYeastBetaGlucan.com , you will receive free, the book, "Beta Glucan: Nature's Secret" by Dr. Vaclav Vetvicka, Professor of Pathology at the University of Louisville. In his book, Vetvicka explains how beta glucan can be beneficial against:

Chronic diseases
Iradiation and/or chemotherapy
Infectious diseases
High cholesterol
Diabetes
Wound healing
Nonspecific stimulation of defense reactions

In addition to the glucan research, Dr. Vetvicka helped to launch glucan in several countries including the USA, France, Turkey and Czech Republic. Dr. Vetvicka is author and co-author of more than 190 peer-reviewed publications, seven books and five international patents.

Chemotherapy Affects Brain Cells and Tissue

2010-10-10T20:14:00.000-05:00

The research team from New York's University of Rochester found that drugs used to destroy cancer cells may actually be more harmful to healthy cells in the brain.

The research which is published in the Journal of Biology carried out tests with three drugs that treat cancer, namely, carmustine, cisplatin and cytosine arabinoside.

Even at very low concentrations all three drugs were toxic to several types of brain cells whose job is to repair other cells in the brain.

Oligodenrocyte cells, which play a key role in the transmission of messages around the nervous system were affected by the three drugs, as well as, damage to the cells in the hippocampus, which is responsible for memory and learning.

This may explain why seizures and memory loss associated with chemotherapy are known side effects. source

October 2010 edition of Breast Cancer Research and Treatment reports researchers at the Indiana University Melvin and Bren Simon Cancer Center used brain imaging to show that changes in brain tissue can occur in breast cancer patients undergoing chemotherapy.

To obtain a baseline, Dr. Andrew Saykin, director of the Indiana University Center for Neuroimaging and a researcher at the IU Simon Cancer Center along with his colleagues studied structural MRI scans of the brain from breast cancer patients following surgery, but before radiation or chemotherapy. Scans were then repeated one month and one year after chemotherapy was completed.

The researchers found gray matter changes were most prominent in the areas of the brain that are consistent with cognitive dysfunction during and shortly after chemotherapy, ranging from subtle effects to more pronounced in others. source

According to the book: Reclaiming Our Health by John Robbins, 75% of oncologists surveyed indicated that "all chemotherapy programs are unacceptable to them and their family members."

For an interesting look at natural alternatives to chemotherapy or in conjunction with chemotherapy, check out:
Bakers Yeast Beta Glucan - Immune supplement
HealthIsInReach - Devices for Cancer Therapy

Common Cold, Flu and Beta Glucan Research

2010-05-01T00:18:00.000-05:00

The common cold, typically caused by human parainfluenza viruses, remains one of the most frustrating of medical illnesses, given its incidence and prevalence. The common cold has significant effects on health, well-being, and productivity.

There are no reliable interventions currently available that significantly protect against influenza infections or prevent the occurrence of this illness. There have been several clinical trials evaluating a variety of dietary supplements for the prevention and treatment of both experimentally induced and naturally occurring colds.

Biological response modifiers such as beta-glucan, specifically Transfer Point Beta-1,3D Glucan, enhance the innate immune response without inducing damaging pro-inflammatory cytokines, and may represent a novel approach to protect against cold and flu pathogens. source

Glucan 300® is Tested for Purity, Potency, and Effectiveness

2010-04-27T20:58:00.000-05:00

Transfer Point Beta-1,3D Glucan (Glucan 300) is Tested for...

Purity:
Each batch of Transfer Point's purified Beta Glucan powder is tested and a Certificate of Analysis is provided. This process ensures that every capsule contains the same pure, potent, effective Beta Glucan that continues to be the number one Beta Glucan in purity. Anything less than a minimum 85% Beta-1,3D Glucan is left behind for "the other guys".

Potency:
The power and potency of the purified powder (Glucan 300) used in Transfer Point's capsules is accomplished by a painstaking series of patented washes. These "washes" leave only the purist of the active ingredient. This makes all the difference between immune system support operating at full effectiveness and one that is compromised with disease and aging challenges.

Effectiveness:
Effectiveness is measured by biological activity. Our 3rd party research proves that Transfer Point Beta-1,3D Glucan out performs the rest. Transfer Point Beta-1,3D Glucan (Glucan 300) tested anywhere from 8-160 times more effective than the leading brand names.

...and comes out on top.

Transfer Point uses only the very best of the best batches (Highest purity, highest potency, and highest biological activity). What does not qualify is sold under many other brands or shipped overseas for redistribution.

For additional information on Transfer Point's Beta Glucan (Glucan 300) visit:
http://www.bakersyeastbetaglucan.com/
877-261-6265

Transfer Point Beta-1,3D Glucan

2010-03-08T01:23:00.001-06:00

Transfer Point Beta-1,3D Glucan for a healthy immune system.

Transfer Point Beta-1,3D Glucan is distributed by:

www.BakersYeastBetaGlucan.com

toll free: 877-261-6265

A Strong Immune System is the First Line of Defense

Beta Glucan Aids Lymphoma Patient

2010-02-07T13:47:00.000-06:00

Lymphoma Patient Testimonial:
Due to my diagnosis of Lymphoma in April 2008, I decided to change my eating habits by eliminating chicken and red meats, reducing sugar and white flour along with foods made with those ingredients and eating more fruits and vegetables.

I thought I was making progress but was informed in Dec. 2008 after undergoing 3 PET Scans over the course of 8 months that my largest retroperitoneal lymph nodes were holding at 19mm and others at 14mm, I needed to do something more, but what?

In Feb. 2009, Nancy, from HealthIsInReach.com, suggested I include Beta-1,3D Glucan, Curcumin, the FIR Dome and the Original Sun Ancon Chi Machine to my regimen which at that time consisted of Vit. D3, Ester C, B Complex, Fish Oil, Resveratrol, Vit. E, Selenium, Sublingual B-12, CoQ10, and Zinc.

One thing to mention at this time, concerns my cholesterol, in June 2008 I had a cholesterol reading of 284, then in Jan. 2009 my cholesterol was 260, but things started happening after taking the Beta-1,3D Glucan, Curcumin and using the FIR Dome and Chi Machine, in May 2009 my cholesterol was down to 161, then in Aug. 2009, my cholesterol came down even further to a reading of 138.

In Oct. 2009 I went through my 4th PET Scan, which revealed shrinkage to my Retroperitoneal lymph nodes. The 19mm lymph nodes diagnosed on Dec. 2008 came in at 10mm and my Dec. 2008 14mm lymph nodes were down to 7mm. I couldn't believe it, I honestly believe the products Nancy suggested has allowed me better PET Scan and cholesterol results.

I can't stop now though, I know I just have to keep plugging away with my daily regimen and who knows, my cancer may be gone in no time, a prayer or two on my behalf wouldn't hurt and would be much appreciated as well. - J.M.

Yeast Beta Glucan is Superior

2010-01-08T00:13:00.000-06:00

Beta glucans can come from yeast, medicinal mushrooms and cereals, such as oats and barley.

Studies show that yeast beta glucan is superior for supporting and enhancing immune function.

Yeast cell walls contain 5 to 10 times the beta glucan content as compared to medicinal mushrooms, resulting in a product with more active ingredient.

Look to Transfer Point's Beta-1,3D Glucan derived from baker's yeast, distributed by BakersYeastBetaGlucan.com, which has the highest purity of carbohydrates and highest concentration of the 1,3 linkage with 1,6 side linkage.

BakersYeastBetaGlucan.com product line:

Beta-1,3D Glucan, Glucan #300, comes in 3 sizes:
Beta-1,3D Glucan 500mg/60capsules (shown)
Beta-1,3D Glucan 500mg/30capsules
Beta-1,3D Glucan 100mg/60capsules

Beta Bitts - Immune support for your pets
Beta Bitts 100mg/60capsules (shown)

Understanding the Immune System

2009-12-08T14:15:00.001-06:00

The U.S. Department of Health and Human Services National Institute of Allergy and Infectious Disease has compiled a publication entitled: Understanding the Immune System - How It Works

This publication, 43 pages in all, is well worth the time to read and study so that you can truly understand the complexity of your immune system.

Excerpt from "Understanding the Immune System", page 1:
The immune system is amazingly complex. It can recognize and remember millions of different enemies, and it can produce secretions (release of fluids) and cells to match up with and wipe out nearly all of them.
The secret to its success is an elaborate and dynamic communications network. Millions and millions of cells, organized into sets and subsets, gather like clouds of bees swarming around a hive and pass information back and forth in response to an infection. Once immune cells receive the alarm, they become activated and begin to produce powerful chemicals. These substances allow the cells to regulate their own growth and behavior, enlist other immune cells, and direct the new recruits to trouble spots. source

Beta Bitts - Immune Support for Animals

2009-11-21T05:40:00.000-06:00

Beta Bitts - Immune Support for Animals
Every living creature has an immune system that needs to be protected and supported. Transfer Point's Beta Bitts, distributed by BakersYeastBetaGlucan.com, does just that for all types of animals, big, small and in-between.

Beta Bitts is a whole food immune supplement purified from the cell wall of bakers yeast referred to as Glucan #300.

The recommended dosage is 1 capsule for every 50 pounds of body weight.

Beta Bitts comes in one size, 100mg, 60 capsules.

A daily serving before meals will help your pet be better prepared to deal with the effects of aging, illness, pollutants, toxins and genetically engineered foods.

Is Beta glucan (Glucan #300) derived from bakers yeast the most effective type of glucan?
Glucans derived from barley, oats, or other grains have been shown to be ineffective as an immune modulator. source

Glucan 300 Considered the Best

2009-11-16T13:55:00.000-06:00

Why is Glucan 300 from Transfer Point considered the best?

Glucan 300® is Tested for…

Purity:
Each batch of Transfer Point’s purified Beta Glucan powder is tested and a Certificate of Analysis is provided. This process ensures that every capsule contains the same pure, potent, effective Beta Glucan that continues to be the number one Beta Glucan in purity. Anything less than a minimum 85% Beta 1,3-D Glucan is left behind for “the other guys”.

Potency:
The power and potency of the purified powder (Glucan 300®) used in Transfer Point’s capsules is accomplished by a painstaking series of patented washes. These “washes” leave only the purist of the active ingredient. This makes all the difference between immune system support operating at full effectiveness and one that is compromised with disease and aging challenges.

Effectiveness:
Effectiveness is measured by biological activity. Our 3rd party research proves that Transfer Point Beta-1,3D Glucan out performs the rest. Transfer Point Beta-1,3D Glucan (Glucan 300®) tested anywhere from 8-160 times more effective than the leading brand names.

…and comes out on top. source

Beta Glucans and Their Immuno-Modulating Properties

2009-11-07T07:09:00.000-06:00

According to Dr. Vaclav Vetvicka beta glucans have very powerful immuno-modulating properties which have been known for over 40 years.

What are beta glucans? Beta glucans are polysaccharides present in a number of cereal grains such as barley, oats, rye, wheat, but also in mushrooms, algae, bakers yeast, and even bacteria.

What is meant by "immuno-modulating properties"? Dr. Vetvicka explains that the beta glucan makes the immune system work at its best, as it will correctly identify your "non self" cells and destroy them. In regards to cancer cells, sometimes our immune system does not always recognize them, due to them being able to disguise themselves. Beta glucan helps the immune system to identify them and destroy them. At the same time, the immune system will be able to recognize your "self" cells, and not attack them.

New Book Release! Beta Glucan: Nature's Secret by Vaclav Vetvicka, Ph.D.

2009-10-24T06:57:00.000-05:00

Just announced! New Book Release:

Beta Glucan: Nature's Secret by Vaclav Vetvicka, Ph.D.

Dr. Vaclav Vetvicka is Professor of Pathology in the Department of Pathology of the University of Louisville in Louisville, KY. He graduated from Charles University in Prague, Czech Republic, with an advanced degree in biology and obtained his Ph.D. from the Czechoslovak Academy of Sciences. His postgraduate training included a stay at the Oklahoma Medical Research Foundation, Oklahoma City, and at the Institute of Microbiology, Prague, Czech Republic.

Dr. Vaclav Vetvicka's main area of research interest focuses on the development of natural immunomodulators.

In addition to the glucan research, Dr. Vetvicka helped to launch glucan in serveral countries including USA, France, Turkey and Czech Republic.

Dr. Vetvicka is author and co-author of more than 190 peer-reviewed publications, seven books and five international patents.

Beta Glucan: Nature's Secret by Vaclav Vetvicka, Ph.D. retails for $21.95 - source

Transfer Point Beta Glucan Purity

2009-10-22T11:27:00.000-05:00

Scientific tests prove that Transfer Point Beta-1,3D Glucan is the best in ash levels (nearly non-detectable) and protein levels.

See for yourself, side by side comparisons of the top five Beta 1,3/1,6 glucan products based upon independent 3rd party analysis is available online at www.bakersyeastbetaglucan.com/TransferPointBetaGlucanPurity.htm

Beta-1,3D Glucan's purification process extensively removes fats, proteins, mannans and other contaminants that others leave in to add weight and to save money, impurities that could cause allergies and other health issues.

The material in each bottle of Transfer Point Beta-1,3D Glucan is independently tested and certified to ensure the material meets or exceeds the requirement of the material used in peer reviewed studies.

On average most other brands require 6-8 times the dose to equal a 1x dose of Beta-1,3D Glucan (Glucan # 300).

Transfer Point Beta-1,3D Glucan Quality Assurance

2009-10-12T14:16:00.000-05:00

Transfer Point Beta-1,3D Glucan contains over 93% pure Beta 1,3/1,6 glucan carbohydrate complex (Glucan # 300), with low fat and protein content. The material in each bottle is independently tested and certified to ensure the material meets or exceeds the requirements of the material used in peer reviewed studies.

Products on the market not substantially purified from baker's yeast or from other sources, such as, grains, mushrooms, oat, barley, require 10, 100, or even 1000-fold doses to induce effect.

These factors combined are considered by many professionals to be the standard requirements for an effective, safe, and nontoxic product.

Transfer Point Beta-1,3D Glucan is manufactured to the strictest standards in state of the art US based manufacturing facilities.

With over 200 patents protecting our beta glucan technology, no other supplier can come close to our superior quality.

Who Will Benefit From Taking Beta Glucan?

2009-10-04T23:33:00.000-05:00

Who will benefit from taking Beta Glucan?

Everyone has the potential to benefit from taking Beta Glucan in the correct dose. Especially people with impaired immunity, or who are susceptible to allergies, autoimmune disease, infectious disease, slow and incomplete healing and cancer, undergoing radiation or chemotherapy, or exposed to radiation from external sources such as UV or electromagnetic fields, or with a high risk of cardiovascular disease.

People under physical or emotional stress, or who have poor nutrition or who consume food preservatives.

Beta Glucan can also help to slow the aging process.

Athletes and those who work out extensively will notice more benefit from their workouts while taking Beta Glucan.

Animals will also benefit from taking Beta Glucan, because their immune systems are very similar to ours. - source

Sources of Beta Glucan

2009-09-30T06:32:00.000-05:00

Sources of Beta Glucan:
A glucan, is a glucan, is a glucan. Or, Maybe not. by A.J. Lanigan

There is a lot of confusion about beta glucans in the dietary supplement market. Which type is best? What is the correct dosage? What determines purity? Although there is a tremendous amount of scientific research supporting the ability of beta glucans to support healthy immune function, not all beta glucans are alike.

There are differences in molecular structure that affect the biological activity. Some products containing beta glucan are supported by credible research, others are not. Levels of purity, which impacts efficacy and perhaps safety, varies greatly among products.

Beta glucans are homologous polysaccharides that enhances the innate immune system and provide broad protection against a wide range of pathogenic challenges.

There's an extensive amount of research to support this finding. Numerous preclinical studies and more than 60 human clinical studies found in over 800 papers show different improvements in disease models.

A number of compounds share the name "beta glucan" even though they are in fact very different.

Beta glucan can come from yeast, medicinal mushrooms and cereals, such as oats and barley.

Beta glucans have different molecular structures that in turn impact biological activity in the body.

Studies show that yeast beta glucan is superior for supporting and enhancing immune function. Yeast cell walls contain 5 to 10 times the beta glucan contents as compared to medicinal mushrooms, resulting in a product with more active ingredient.

To understand yeast beta glucans and their biological activity, it's important to know where they come from and how they are manufactured.

Outside of the baker's yeast cell is a fibrillar mannoprotein layer that masks and presents a barrier to exposure of the beta 1,3 glucan to the external environment. Beneath the mannoprotein layer are layers of beta glucan and beta glucan chitin, which is outside the plasma membrane. It's this beta glucan layer that actually provides the shape and structural rigidity of the yeast cell. The beta glucan in yeast is analogous to cellulose in a tree. Both provide structural support.

There are a number of products containing beta glucan on the market today. Which is best? What should customers look for?
Here are some things to consider:
1) Look for products that are backed by credible science.
2) Loof for products that are manufactured by those who insist on a certificate of analysis, which clearly shows the actual potency and purity of the product. Evidence of levels of biological activity remove all doubt as to which compound can and will do the job.
3) Patents that prove the product is the genuine article, not a knock-off product.

So what is the Best Beta Glucan for your immune system?
It is Transfer Point Beta-1,3D Glucan from baker's yeast that has the highest purity of carbohydrates and highest concentration of the 1,3 linkage with 1,6 side linkage.

The Immune Response Enhanced by Beta-1,3D Glucan - pg.1

2009-09-26T00:42:00.000-05:00

The Immune Response Enhanced by Beta-1,3D Glucan by A.J.Lanigan - pg.1

The immune response begins when invaders like viruses enter the body. White blood cells, called macrophages, encounter the invader and consume it. The macrophage does not care what the invader might be. It only knows self or non-self. Meanwhile, other viruses look for nearby cells to infect. Beta-1,3D Glucan, an extract from the cell wall of a baker's yeast, turns the "Woody Allen cells" into "Schwartzenagger cells." This allows your immune system to be "all that it can be". Beta-1,3D Glucan modulates and potentiates the macrophage and keeps it in a more prepared state. With this balancing effect, all subsequent immune response improves. The beta glucan and the macrophages are oblivious to the type of invader or the health of the host. Again, the macrophage only knows self vs. non-self. The glucan treated host will enjoy an increase in its arsenal against unwanted offenders.

Next, the macrophage digests the virus and displays pieces of the virus (antigens) on its surface. Antigens may be any substance introduced into the body that the immune system recognizes as non-self. Nearby cells may become infected by the attacking viruses. In a healthy immune system, these infected cells will come under attack, be destroyed, and be removed before they can be used to spread the illness.

Unique among the different helper T cells (another class of white blood cells) in the body, one particular helper T cell now recognizes the antigen displayed and binds to the macrophage. There are at least two subsets of the helper T cells, the Th1 and the Th2. They make the decisions as to what type response will be ordered. Up and down regulatory factors transmitted by this pair of cells (macrophage + T helper) provide many variations for dealing with the invaders.

This union stimulates the production of chemical substances - such as interleukin-1 (IL-1) and tumor necrosis factor (TNF) by the macrophage, and interleukin-2 (IL-2) and gamma interferon (IFN-y) by the T cell - that allow intercellulor communication. Theses cytokines/lymphokins (fax messages) are required for T cell activation and response. Mere activation is not enough. The Antigen Presenting Cell (APC), depending on the type (MHC I or II) of presentation gives co-stimulation (a second go-ahead signal). CD28 (blood test) reflects this co-stimulation and activation process. - source

The Immune Response Enhanced by Beta-1,3D Glucan - pg.2

2009-09-26T00:20:00.000-05:00

The Immune Response Enhanced by Beta-1,3D Glucan by A.J.Lanigan - pg.2

As part of the continuing process, IL-1 helps activate B and T cells; IL-2 instructs other helper T's and a different class of T cells, the killer T's (CTLs or cytotoxic T lymphocytes), to multiply. The proliferating helper T's in turn release substances that cause B cells to multiply and produce antibodies. B cells are prepared to recognize antigen without preprocessing. The T cell cannot recognize antigen in its natural state. It must first be broken down and the fragments bound to a Major Histocompatibility Complex (MHC) molecule by the APC. The macrophage is an APC. Glucan causes its receptor sites (key slots) to be released for these presentation chores.

The killer T cells (trained assassins) now begin shooting holes in cells that have been infected by viruses or other pathogens. The killer T cell (CTL or cytotoxic T lymphocyte) becomes a "trained assassin". They respond to the MHC I complex, which is found on almost all body cells. The CTL has the ability to seek and destroy infected human cells in a specific manner. With the injection of powerful chemicals, these infected cells are killed before they can be used to spread a disease. Natural Killer (NK) cells are large, granule-filled lymphocytes that take on tumor cells and infected body cells. They are known as "natural" killers because they attack without first having to recognize specific antigens. Like the macrophage, if it is not "self", it will proceed to kill. NK cells and CTLs both kill on contact. The killer binds to the target, aims its weapons and then releases a lethal burst of chemicals to punch holes in the target. - source

The Immune Response Enhanced by Beta-1,3D Glucan - pg.3

2009-09-25T23:52:00.000-05:00

The Immune Response Enhanced by Beta-1,3D Glucan by A.J.Lanigan - pg.3

When a Class II MHC molecule is presented by the APC, the B cell/antibody process begins. This is the humoral side of the immune system. The antibodies released by the B cells bind to antigens on the surfaces of free-floating viruses. Besides making it easier for macrophages to destroy viruses, this binding signals blood components called complement to puncture holes in the viruses. The Complement System is made up of 25 proteins that work with the antibodies to destroy invaders. They facilitate phagocytosis (eating by phagocytes) or they directly puncture the invader's cell membrane. C3 is the key protein that triggers the "complement cascade". This cascade results into a "membrane attack complex" that literally blasts a hole into the antibody marked prey. Fragments thrown off by this process bring into play mast cells and basophils. By releasing their chemical contents, they produce the rediness, warmth, and swelling of the inflammatory response.

Finally, as the infection is brought under control, the activated T and B cells are turned off by suppressor T cells (a T-8 subset). However, a few "memory cells" (another T-8 subset) remain behind to respond quickly if the same virus attacks again. Immunologists believe that the body fights cancer in much the same way it seeks to eliminate viruses. Further study of the immune system is expected to reveal ways to bolster it, allowing the body to become a more active partner in the fight against cancer. - source

Autoimmune Diseases and Beta Glucan

2009-09-24T06:04:00.000-05:00

Balance of cytokine production is important. Autoimmune diseased patients frequently display low IL-2 and high gamma-Interferon. Absolute causes are not established but there are strong indications towards viruses and environmental factors (i.e., sunlight, chemicals, and certain drugs that alter recognized self to non-self cell types). Due to the high incidence of autoimmune disease in women, heredity and sex hormones are suspected since Major Histocompatibility Complex (MHC) responses are relative to certain genes.

There are numerous studies showing the safety and effectiveness of Beta-1,3D Glucan in a host for immune bolstering, immune dysfunction, immune dysregulation and last but not least, the selective lowering of LDL cholesterol.

In the area of autoimmune disease, the removal of diseased cells, debris, and harmful molecules from the body and blood are important. Beta-1,3D Glucan derived from the cell walls of bakers yeast plays a role here. Scavenging and debris cleansing abilitites of the properly modulated macrophage can assist these processes.

In various parts of the body, macrophages may be called:

Alveolar cells - lungs
Interdigitating cells - various
Kupffer cells - liver
Langerhans cells - skin
Mesangial cells - kidneys
Microglial cells - brain
Monocyte cells - blood
Neutrophil cells - various
Serosal cells - endothelial layer
Synovial cells - joints

To maximize your uptake of the Beta-1,3D Glucan, it should always be taken on an empty stomach. Wait at least 30 minutes before eating or drinking anything. A small amount of pure water should be used to swallow the capsule. (No coffee, tea, juice, etc.) - source

How Much Transfer Point Beta Glucan Should I Take?

2009-09-13T17:34:00.000-05:00

How much Transfer Point Beta-1, 3D Glucan should I take?
That depends on your immune system*, what you are dealing with, and your body weight. Everyone's immune system is different. Your immune system is also changing constantly. The information below will give you some guidance.

Current research suggests an effective dosage to range from 2mg-25mg of Beta Glucan per kilogram(kg) of weight. Depending on your current situation, you may benefit taking more or less of a daily dose.

To find your optimum dose, first convert pounds to kilograms (2.2 lbs. = 1 kg). For example, if you weighed 220 lbs., then you would weigh 100kg. This means you would want to take at least 200mg of Beta Glucan everyday, but no more than 2500mg everyday (research shows if you were to take more than 25mg per kilogram, there would be no added benefit).

*Remember, it is your immune system, not Beta Glucan that addresses any problems.

To maximize your uptake of the Transfer Point Beta-1, 3D Glucan, you should always take it on an empty stomach. Wait at least 30 minutes before eating or drinking anything. A small amount of pure water should be used to swallow the material. (No coffee, tea, juice, etc.)

Normally, simple sugars would be broken down in the digestive system, converted to glucose, and used for energy. This does not occur with a long chain polysaccharide like Beta-1,3D Glucan. The polysaccharide is carried across the lining of the small intestine into the lymphatic system. It is lined with enterones and enterocytes. They produce a sticky substance on their surface called glycocalix or “the fuzz”. In this glycocalix, binding sites (receptors) sit ready to grab the Beta-1,3D Glucan. From the lymphatic system, the Beta-1,3D Glucan is carried into the blood stream. This process is called endocytosis or pinocytosis. – A.J. Lanigan, Formulator Transfer Point Beta-1,3D Glucan

Study Shows Transfer Point's Beta-1,3D Glucan Superior Brand

2009-09-10T15:38:00.000-05:00

For more than forty years, well documented research has shown that Beta-1,3D Glucan is a safe and beneficial immune modulator. Used in many commercial dietary supplement products, Beta Glucan is a key ingredient that manufacturers and formulators rely upon. But as it is known, not all products are the same or deliver on their promises. Just published research from the Journal of the American Nutraceutical Association shows a side-by-side comparison of commercially available glucans. Research conducted at the University of Louisville by Drs. Vaclav Vetvicka and Jana Vetvickova provided significant insights on Beta Glucan quality that should clear up much of the confusion about glucans and immune supplements in general. Bottom line - Transfer Point's Beta Glucan product came out among the best. The findings were published in JANA Volume 10, Number 2, 2007.

The study looked at numerous concentrations and routes of administration - including oral, intraperitoneal, subcutaneous and intravenous applications. With more than one hundred samples from the United States alone, products tested also came from Europe, Southeast Asia and Japan. Soluble, insoluble, grain, mushroom, seaweed and yeast were among the groups compared.

The final analysis revealed that Glucan #300, purchased from Transfer Point, Inc. of Columbia, S.C. showed not only a broad range of action, but in all areas tested (except antibody formation, where it was #2) was the biologically most relevant immunomodulator.

A.J. Lanigan, the innovator of Transfer Point's product states: "We have confirmation from esteemed academic and scientific institutions like the University of Louisville and top Beta Glucan researchers like Drs. Vaclav Vetvicka and Jana Vetvickova that our products meet the highest quality standards and provide the benefits they promise. The consumer can know with confidence we offer one of the most biologically active ingredients for the immune system in a dietary supplement product."

Beta Glucan - Shown to Directly Increase Hematopoiesis (bone marrow producing stem cells)

2009-09-06T00:11:00.000-05:00

Hematopoiesis is the process by which your bone marrow produces stem cells. Stem cells are one of the most vital needs of your immune system, because stem cells ultimately become white blood cells. Specialized types of white blood cells are called phagocytes; these include macrophages, neutrophils, and eosenophils. One function of these phagocytes is to engluf invaders (or any foreign substance) immediately, without question. This process is called phagocytosis.

Phagocytosis has also been tested and shown to be enhanced by Transfer Point's Beta Glucan. The phagocyte's ability to engulf foreign substances is very important. The faster phagocytosis happens, the more debris the phagocyte can destroy. When a phagocyte digests an invader, it notifies the proper authorities (T cells), to let them know there is a foreign substance present. The T cells decide the best action to pursue in order to relieve the body of this foreign substance. Once the phagocyte presents the debris of the invader, the T cells have a couple options.

If the T cell initiates a cell mediated immune response, all phagocytes that have flocked to the site of infection are assisted by other specific white blood cells. This charge of cells is called chemotaxis. Chemotaxis has been tested and shown to be enhanced by Transfer Point's Beta Glucan. When the phagocytes reach the site of invasion, they produce reactive oxygen intermediates (ROIs) and reactive nitrogen intermediates (NOIs). These ROIs and NOIs include hydrogen peroxide (H2O2) and nitric oxide (NO), and are very important in helping the phagocytes to rapidly destroy the invader. Transfer Point's Beta Glucan has been tested and shown to help phagocytes produce more ROIs and NOIs. Therefore, the faster the phagocytes reach the site of invasion, and use ROIs and NOIs, the faster the intruder's position is compromised.

However, if the T cell initiates a humoral immune response, B cells are notified to create plasma cells, which create antibodies to fight the infection. These antibodies are actually chemicals designed to tag a specific invader, and take about 21 days to fully develop. When the antibodies are ready, they are sent out to target the specific substance for which they are made. Until these antibodies are ready, it is up to the innate immunity to directly come in contact, hand to hand combat, and ultimately engulf the intrusive substance.

Innate immunity is what keeps you alive, until acquired immunity is established. In some cases, a person's immune system programs itself to rely too much on a humoral (antibody) response verses a cell mediated immune response. Transfer Point's Beta Glucan has been tested and shown to correct an over-shifted humoral response to a cell mediated immune response. Anecdotal evidence and theory suggest this is helpful in allergies, autoimmune disease, and cancer.

Researchers Share Comments About Beta-1,3D Glucan

2009-09-05T01:27:00.000-05:00

"The current study represents the first demonstration that a specific form of Beta-1,3D Glucan can enhance the immune system's ability to kill anthrax spores, and that it can do so orally." Gary R. Ostroff, PhD, at the 224th national meeting of the American Chemical Society

The U.S. Armed Forces Radiobiology Research Institute Study found that systematic Beta-1,3D Glucan synergizes with cytokine and growth factor stimulation of hemotopoeisis (white blood cell formation) in the bone marrow following myelosupression. Initial preclinical results demonstrate that oral Beta glucan also provides a radiation protective effect.

"In one study, oral Beta-1,3D Glucan administered alone reduced tumor weight by nearly half. But when used in conjunction with a monoclonal antibody, the average tumor weight shrank by more than 80%." Gordon Ross, PhD, University of Louisville School of Medicine

Beta glucan has been proven to be effective when administered orally or intravenously, however, the latter would require daily visits to a physician. When taken orally, the macrophage obtains maximum activity and effectiveness after about 72 hours, then again reaches normal activity after about 144 hours.

"As it is a natural substance, there are no side effects and there is no danger of overdose. Clearly Beta Glucan is a natural, safe, specific, and highly effective way to keep our immune system healthy." Dr. Vaclav Vetvicka

Is Beta-1,3D Glucan Effective?

2009-09-02T20:41:00.000-05:00

The immune-enhancing properties of yeast cell walls were reported in 1939.
In the 1960's the researchers identified beta 1,3 glucan as the immune stimulating component.

Check out the official abstracts (reprinted in their entirety) or representative published studies conducted on beta 1,3 glucan. These abstracts are intended to provide a balanced view of the available scientific information related to beta glucan. Beta Glucan Research

Beta-1,3D Glucan - A Product Proven to Benefit Your Immune System

2009-09-01T18:53:00.000-05:00

Beta-1,3D Glucan, a product proven to benefit your immune system, backed by scientific research from universities and teaching hospitals you can trust.

University tested to be 8-160 times more effective when compared to dozens of other "immune products" - source
Pre-Clinical evidence shows rapid recovery from radiation and chemotherapy
Protected by over 200 US and International patents covering processes of manufacture, composition, and uses of Beta glucan from Baker's Yeast
The only Beta glucan proven in vivo to enhance immune protection against community and hospital acquired infections
Safe, natural and free from unwanted contaminants that could give rise to allergies or exaggerate certain autoimmune conditions
Tested for safety and efficacy in human clinical trials
Orally absorbed and distributed throughout the immune system

Transfer Point's Beta Glucan Researched by Prestigious Universities

2009-08-30T23:31:00.000-05:00

Transfer Point's Beta Glucan has been researched and documented by some of the most prestigious universities in the world:

Auburn University
Brown University
Cornell University
Memorial Sloan Kettering Cancer Center
North Carolina A & T State University
University of Louisville
University of Massachusetts
University of Minnesota
U.S. Armed Forces Radiobiology Research Institute
Defense Research Establishment in Suffield, Cananda

"As it is a natural substance, there are no side effects and there is no danger of overdose. Clearly Beta glucan is a natural, safe, specific, and highly effective way to keep our immune system healthy." - Dr. Vaclav Vetvicka, University of Lousiville

A Strong Immune System is the First Line of Defense

2009-08-28T06:44:00.000-05:00

A strong immune system is the first line of defense against the daily assaults of stress, poor nutrition, and environmental toxins.

A key to defending our body is making sure our immune system is strong and able to handle what comes it's way. There are supplements on the market that claim to do amazing things, but what you want is something that works. Many dietary supplements include nutrients that are based more on marketing buzz than they are on hard science. And even when they are based on science, many formulas don't include enough of the active nutrient to make a difference. You need a supplement that is backed by solid science - not anecdotal evidence, old wives tales, or flawed research.

We have found that Transfer Point's Beta Glucan has the science and research behind it's product, every single batch of Beta Glucan that Transfer Point produces is tested for purity and quality. Each batch is tested by a widely respected, independent, third party laboratory, and the certificate of analysis is printed on every bottle.

Transfer Point's Beta-1,3D Glucan is derived from the cell walls of baker's yeast (Saccharomyces cerevisiae) and contains over 93% pure Beta 1,3/1,6 glucan carbohydrate complex, with low fat and protein content. Transfer Point's Beta Glucan has been subjected to rigorous studies at numerous universities (Auburn University, Brown University, Cornell University, University of Louisville, University of Massachusetts, University of Minnesota) and has been scientifically proven to maintain and support a healthy immune response. On the other hand, glucans derived from barley, oats, or other grains have been shown to be ineffective as an immune modulator.

The immune-enhancing properties of yeast cell walls were reported in 1939, but it wasn't until the 1960's that researchers identified Beta 1, 3D glucan as the key. Since then, scientists at some of the world's pre-eminent universities and research institutions have conducted more than 800 Beta 1, 3D glucan studies in animals and humans. This research confirms that Beta 1, 3D glucan produces multiple broadscale effects that strengthen the vitality of the immune system.

Dr. Vaclav Vetvicka from the University of Louisville said, "For over 40 years, beta glucans have been thoroughly tested on everything from earthworms to human beings...even plants."

A.J. Lanigan, Manufacturer and Formulator of Transfer Point's Beta Glucan comments, "Nothing can take the place of a healthy immune system. When it functions properly, the body has all the ammunition it needs to ward off disease and combat illness."

Maintaining one's health is critical in periods of stress. The health conscious consumer will know the value of supporting their immune system during these times.

Beta Glucan Helps The Immune System Work Better

2009-08-27T14:22:00.000-05:00

Transfer Point Beta Glucan is an immune modulator which helps the immune system work better, it will not either boost or suppress the immune system.

Transfer Point Beta Glucan has been scientifically proven to both maintain and support a healthy immune response.

Transfer Point Beta Glucan works by activating immune cells known as macrophages, neutrophils and natural killer (NK) cells. These are your immune system's first line of innate defense. They are responsible for finding, identifying, and consuming foreign substances in the body. Macrophages also control the activities of other important cells in the immune system.

Recently published studies by Beta glucan and immunology research experts at the University of Louisville, Drs. Vaclav Vetvicka and Jana Vetvickova, demonstrated the superiority of Transfer Point's Beta-1,3D Glucan as compared to others on the market. The science revealed that purity of the product makes all the difference clinically. The purer the Beta glucan, the more profound the clinical results were in the studies presented. Transfer Point's highly purified product was found to be the most active in this group. Here are the results:

The strongest healthy immune response of phagocytosis and massively high cytokine (IL-2) levels as compared to all other major brands.
Healthy blood sugar level support
Healthy cholesterol level suport

All of this was demonstrated at relatively low doses of Glucan # 300 per day as compared to massive doses of other competitors. Transfer Point's Beta-1,3D Glucan packs the biggest support for a healthy immune system at a cost that the competition cannot meet. source